Inauguration: 7.5 Things You Should Have Seen

A presidential inauguration is a big, long event that lasts all day and into the night–and who has time to really watch it? People have jobs, ones that don’t let you off for a federal holiday.

Everyone (or, at least, some) will be talking about it, which means potential embarrassment for anyone who doesn’t know what happened. Thankfully, ABC employs  news professionals stationed in Washington, D.C., to pay attention to these kinds of things and boil off some of the less noteworthy or interesting stuff, presenting you with short videos of everything that really mattered. Or at least the things a lot of people were talking about.

A full day of paying attention to President Obama’s second Inauguration leads one of those professionals to offer these 7 1/2 things:

1. Beyonce Sang the National Anthem

Boy, howdy! Did she ever? Beyonce has essentially become the Obama’s go-to female performer: She recorded a music video for Michelle Obama’s “Let’s Move” initiative in 2011, and she performed at the president’s last inauguration in 2009. Her velvety, soulful “Star Spangled Banner” is getting good reviews.

2. Kelly Clarkson Also Sang

Kelly Clarkson is not as “in” with the First Couple as Beyonce seems to be, but they let her sing “My Country ‘Tis of Thee,” and she did a pretty good job with it. This was kind of weird, though, because at one point she said she loved Ron Paul, although she later said she would vote for Obama.

3.  Obama Talked About Gay Rights

This may not seem shocking since more than half the country, including President Obama, supports gay marriage. But the president made a point of mentioning gay rights during his speech, equating the struggles of the LGBT community with those of  past civil rights movements, and in doing so made history.

He name-checked Stonewall, the New York City bar that was raided by police in 1969 sparking riots to protest the anti-gay crackdown. And he actually used the word “gay”: “Our journey is not complete until our gay brothers and sisters are treated like anyone else under the law – for if we are truly created equal, then surely the love we commit to one another must be equal as well,” Obama said in his address.

Plenty of inaugural addresses have been chock full of rhetoric about freedom and equality, but in the last four years, the political culture surrounding gay rights has changed significantly, as more states legalized same-sex marriage and as broad swaths of the country got more comfortable with homosexuality in general. Obama’s “evolution” on gay marriage, and now his inaugural address, have helped signify that change.

4. Joe Biden Made Jokes and Shook Hands With People

Could we expect anything less?

Here’s how the Vice President toasting Sen. Chuck Schumer instead of President Obama at the big luncheon:  ”I raise my glass to a man who never, never, never operates out of fear, only operates out of confidence, and a guy–I’m toasting you, Chuck.” Watch it:

And here he is, scurrying around and jovially shaking hands with people along the parade route:

5. Richard Blanco Read a Poem That Was Sort of Whitman-esque, But Not Entirely

Cuban-born Richard Blanco became America’s first openly gay, Latino Inauguration poet. He read a nine-stanza poem entitled “One Today,” which set a kind of unifying American tableau scene.

6. Obama and Michelle Walked Around Outside The Limo

President Obama walked part of the parade route, from the Capitol to the White House, with Michelle. They waved to people. It is not entirely abnormal for a president to do this at an inaugural parade. But they walked quite a ways.

7. John Boehner: ‘Godspeed’

The speaker of the House presented American flags to Obama and Biden, telling them: “To you gentlemen, I say congratulations and Godspeed.”

7 1/2. Sasha and Malia Were There. 

Obama’s daughters, Sasha and Malia, were there. They didn’t really do much, but they did wear coats of different shades of purple that got a lot of  attention on Twitter.

Reports of the daughters looking at smartphones and applying lip gloss highlighted their day. As did this .gif of Sasha yawning.

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Algeria toll rises as attack claimed for al Qaeda

ALGIERS, Algeria (Reuters) - The death toll has risen to at least 48 hostages killed during a four-day siege at a gas plant deep in the Sahara as a veteran Islamist fighter claimed responsibility on behalf of al Qaeda for the attack.

Prime Minister Abdelmalek Sellal is expected to give details at a Monday news conference about one of the worst international hostage crises in decades, which left American, British, French, Japanese, Norwegian and Romanian workers dead or missing.

A security source said on Sunday Algerian troops had found the bodies of 25 hostages, raising the number of militants and their captives killed to at least 80. He said six militants were captured alive and troops were still searching for others.

One-eyed veteran Islamist fighter Mokhtar Belmokhtar claimed responsibility on Sunday for the attack on behalf of al Qaeda.

"We in al Qaeda announce this blessed operation," he said in a video, according to Sahara Media, a regional website. He said about 40 attackers participated in the raid, roughly matching the government's figures for fighters killed and captured.

The fighters swooped out of the desert and seized the base on Wednesday, capturing a plant that produces 10 percent of Algeria's natural gas exports, as well as a nearby residential barracks.

They demanded an end to French air strikes against Islamist fighters in neighboring Mali that had begun five days earlier. However, U.S. and European officials doubt such a complex raid could have been organized quickly enough to have been conceived as a direct response to the French military intervention.

The siege turned bloody on Thursday when the Algerian army opened fire saying fighters were trying to escape with their prisoners. Survivors said Algerian forces blasted several trucks in a convoy carrying both hostages and their captors.

Nearly 700 Algerian workers and more than 100 foreigners escaped, mainly on Thursday when the fighters were driven from the residential barracks. Some captors remained holed up in the industrial complex until Saturday when they were overrun.

The bloodshed has strained Algeria's relations with its Western allies, some of whom have complained about being left in the dark while the decision to storm the compound was being taken. Nevertheless, Britain and France both defended the Algerian military action.

"It's easy to say that this or that should have been done. The Algerian authorities took a decision and the toll is very high but I am a bit bothered ... when the impression is given that the Algerians are open to question," said French Foreign Minister Laurent Fabius. "They had to deal with terrorists."

British Prime Minister David Cameron said in a televised statement: "Of course people will ask questions about the Algerian response to these events, but I would just say that the responsibility for these deaths lies squarely with the terrorists who launched this vicious and cowardly attack.

"We should recognize all that the Algerians have done to work with us and to help and coordinate with us. I'd like to thank them for that. We should also recognize that the Algerians too have seen lives lost among their soldiers."

Algeria had given a preliminary death toll of 55 people killed - 23 hostages and 32 militants - on Saturday and said it would rise as more bodies were found.

The security source said that toll did not include the bodies of 25 hostages found on Sunday, which meant the total number of captives killed - foreign and local - was at least 48. The search was not over, and more could yet be found, he said.

Among foreigners confirmed dead by their home countries were three Britons, one American and two Romanians. The missing include at least 10 Japanese, five Norwegians, three other Britons, and a British resident. The security source said at least one Frenchman was also among the dead.

LAST WORDS?

Alan Wright, now safe at home in Scotland, said he had escaped with a group of Algerian and foreign workers after hiding for a day and a night. While hiding inside the compound, he managed to call his wife at home with their two daughters.

"She asked if I wanted to speak to Imogen and Esme, and I couldn't because I thought, I don't want my last ever words to be in a crackly satellite phone, telling a lie, saying you're OK when you're far from OK," he recalled to Sky News.

Despite the incident, Algeria is determined to press on with its energy industry. Oil Minister Youcef Yousfi visited the site and said physical damage was minor, state news service APS reported. The plant would start back up in two days, he said.

The Islamists' assault has tested Algeria's relations with the outside world and exposed the vulnerability of multinational oil operations in the Sahara.

Algeria, scarred by the civil war with Islamist insurgents in the 1990s which claimed 200,000 lives, insisted from the start of the crisis there would be no negotiation in the face of terrorism.

France especially needs close cooperation from Algeria to crush Islamist rebels in northern Mali.

(Additional reporting by Balazs Koranyi in Oslo, Estelle Shirbon and David Alexander in London, Brian Love in Paris and Daniel Flynn in Dakar; Writing by Peter Graff; Editing by Sophie Hares and Myra MacDonald)

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Tennis: Kuznetsova upsets Wozniacki at Australian Open

MELBOURNE: Two-time Grand Slam winner Svetlana Kuznetsova upset Danish 10th seed and ex-world number one Caroline Wozniacki in a tense three-set battle to make the Australian Open last eight on Monday.

The experienced Russian won 6-2, 2-6, 7-5 and will meet either top seed Victoria Azarenka or Russian Elena Vesnina in the quarter-finals.

It was a courageous win by Kuznetsova, who at 75 is the lowest ranked player left in the tournament after an injury to her right knee forced her to miss a big chunk of 2012, spending two months on crutches.

The injury meant she missed all post-Wimbledon events last year including the US Open, which ended her streak of 40 straight Grand Slam appearances dating back to 2002 at Flushing Meadow.

But Kuznetsova, who won the 2004 US Open and 2009 French Open, said she was feeling fresh again and delighted to be in the quarter-finals.

"I'm really happy with the result because in the second set I got stuck a bit," she said. "But I came out fighting in the third, and it's great.

"After 10 years of travelling I was getting tired," she added of her time on tour. "But I'm feeling fresh again and very happy to be in the quarter-finals because I struggled last year."

It was Wozniacki who was struggling on Monday. Her preparations for Melbourne were hurt by going out early at both the Brisbane and Sydney International tournaments, and her lacklustre form continued in Melbourne.

It was Kuznetsova who knocked her out of Sydney in the second round and while both players held their opening serves, the Russian put the Dane under pressure with some aggressive groundstrokes in the third game.

She won a crucial advantage on the second break point to go 2-1 ahead and consolidated the break by holding serve.

Kuznetsova kept pressing and got a second break in the seventh game when Wozniacki smashed a forehand into the net. She served out for the set but against the run of play, Wozniacki broke for a 2-0 lead in the second set.

The Russian lost her momentum and the Dane pushed on to get another break and take the set in 33 minutes.

It set up a tense decider and the Russian came out refreshed, taking a break for 2-1 with Wozniacki's frustration clear as she slammed her racquet to the ground.

The Dane dug deep to immediately break back as Kuznetsova lashed a forehand wide. The set became a battle with each player desperately trying to outsmart the other.

Kutznetsova finally got the breakthrough when Wozniacki netted a forehand on her serve to hand the Russian a 5-4 lead and she served out for the match.

- AFP/al

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Yannick's mother wants to visit son, but has no money

PATIALA: After treatment for about six months in a private hospital here, there is slight improvement in the health of Burundi student, Yannick Nihangaza, who was brutally attacked in Jalandhar in April, but the long stay of his father in Patiala has badly affected the financial health of the family.

Yannick's mother and younger brother want to come to Patiala to see their recovering family member, but don't have money left to pay for travel expenses.

"My wife Jotisean and younger son Landri want to come here. They need $3000 for this. But since I am staying here after quitting my job last April, my wife and son don't have money to pay for their travel expenses," said Nestor, father of Yannick.

On April 22 last year, the 23-year-old BSc computer science student of a private university had gone to attend a party in Jalandhar when some unidentified persons attacked him, severely beat him up and threw him on roadside. Yannick was hit on the head and had slipped into coma and was taken to a hospital by some unidentified persons. Later, in view of his serious condition, he was referred to a private hospital in Patiala, where he remained in coma till the end of November. He regained consciousness in the last week of November.

Getting information about the serious condition of his son, Nestor reached Patiala on April 24 and since then, he has been staying here in a room in the hospital to take care of his son.

Nestor worked with an NGO in Burundi and had to quit his job as the condition of his son worsened.

The mother of Yannick had come to Patiala in August 2012 and stayed here for 20 days. In the absence of her husband and any other financial support from anyone, all the family burden has now fallen on her younger son Jotisean, who has been working in a private company.

"She has been calling me almost everyday to get the latest news about Yannick's health. Sometimes, she starts crying over phone. She stayed here for 20 days in last August, but Yannick did not open his eyes even for once. As he has now started opening eyes, she wants to see him," said Nestor, while sitting with his daughter Fiona, who had come to Patiala some days back.

"I am waiting for the day when my son will get well and I will be able to take him back to unite him with his mother and younger brother," said Nestor.

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Flu season fuels debate over paid sick time laws

NEW YORK (AP) — Sniffling, groggy and afraid she had caught the flu, Diana Zavala dragged herself in to work anyway for a day she felt she couldn't afford to miss.

A school speech therapist who works as an independent contractor, she doesn't have paid sick days. So the mother of two reported to work and hoped for the best — and was aching, shivering and coughing by the end of the day. She stayed home the next day, then loaded up on medicine and returned to work.

"It's a balancing act" between physical health and financial well-being, she said.

An unusually early and vigorous flu season is drawing attention to a cause that has scored victories but also hit roadblocks in recent years: mandatory paid sick leave for a third of civilian workers — more than 40 million people — who don't have it.

Supporters and opponents are particularly watching New York City, where lawmakers are weighing a sick leave proposal amid a competitive mayoral race.

Pointing to a flu outbreak that the governor has called a public health emergency, dozens of doctors, nurses, lawmakers and activists — some in surgical masks — rallied Friday on the City Hall steps to call for passage of the measure, which has awaited a City Council vote for nearly three years. Two likely mayoral contenders have also pressed the point.

The flu spike is making people more aware of the argument for sick pay, said Ellen Bravo, executive director of Family Values at Work, which promotes paid sick time initiatives around the country. "There's people who say, 'OK, I get it — you don't want your server coughing on your food,'" she said.

Advocates have cast paid sick time as both a workforce issue akin to parental leave and "living wage" laws, and a public health priority.

But to some business owners, paid sick leave is an impractical and unfair burden for small operations. Critics also say the timing is bad, given the choppy economy and the hardships inflicted by Superstorm Sandy.

Michael Sinensky, an owner of seven bars and restaurants around the city, was against the sick time proposal before Sandy. And after the storm shut down four of his restaurants for days or weeks, costing hundreds of thousands of dollars that his insurers have yet to pay, "we're in survival mode."

"We're at the point, right now, where we cannot afford additional social initiatives," said Sinensky, whose roughly 500 employees switch shifts if they can't work, an arrangement that some restaurateurs say benefits workers because paid sick time wouldn't include tips.

Employees without sick days are more likely to go to work with a contagious illness, send an ill child to school or day care and use hospital emergency rooms for care, according to a 2010 survey by the University of Chicago's National Opinion Research Center. A 2011 study in the American Journal of Public Health estimated that a lack of sick time helped spread 5 million cases of flu-like illness during the 2009 swine flu outbreak.

To be sure, many employees entitled to sick time go to work ill anyway, out of dedication or at least a desire to project it. But the work-through-it ethic is shifting somewhat amid growing awareness about spreading sickness.

"Right now, where companies' incentives lie is butting right up against this concern over people coming into the workplace, infecting others and bringing productivity of a whole company down," said John A. Challenger, CEO of employer consulting firm Challenger, Gray & Christmas.

Paid sick day requirements are often popular in polls, but only four places have them: San Francisco, Seattle, Washington, D.C., and the state of Connecticut. The specific provisions vary.

Milwaukee voters approved a sick time requirement in 2008, but the state Legislature passed a law blocking it. Philadelphia's mayor vetoed a sick leave measure in 2011; lawmakers have since instituted a sick time requirement for businesses with city contracts. Voters rejected a paid sick day measure in Denver in 2011.

In New York, City Councilwoman Gale Brewer's proposal would require up to five paid sick days a year at businesses with at least five employees. It wouldn't include independent contractors, such as Zavala, who supports the idea nonetheless.

The idea boasts such supporters as feminist Gloria Steinem and "Sex and the City" actress Cynthia Nixon, as well as a majority of City Council members and a coalition of unions, women's groups and public health advocates. But it also faces influential opponents, including business groups, Mayor Michael Bloomberg and City Council Speaker Christine Quinn, who has virtually complete control over what matters come to a vote.

Quinn, who is expected to run for mayor, said she considers paid sick leave a worthy goal but doesn't think it would be wise to implement it in a sluggish economy. Two of her likely opponents, Public Advocate Bill de Blasio and Comptroller John Liu, have reiterated calls for paid sick leave in light of the flu season.

While the debate plays out, Emilio Palaguachi is recovering from the flu and looking for a job. The father of four was abruptly fired without explanation earlier this month from his job at a deli after taking a day off to go to a doctor, he said. His former employer couldn't be reached by telephone.

"I needed work," Palaguachi said after Friday's City Hall rally, but "I needed to see the doctor because I'm sick."

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Associated Press writer Susan Haigh in Hartford, Conn., contributed to this report.

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Follow Jennifer Peltz at http://twitter.com/jennpeltz

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Obamas Share the Love, Even for Michelle's Bangs

Jan 20, 2013 10:49pm

(Charles Dharapak/AP Photo)

President Obama used the first public remarks of his second term to address what he called the “most significant” event of this weekend: his wife’s much-talked-about new haircut.

“I love her bangs,” Obama told supporters at an inaugural reception at the National Building Museum. “She looks good. She always looks good.”

First lady Michelle Obama, wearing a black sequined cocktail dress and showcasing her new hairdo, also heaped compliments on her husband.

“Let me tell you, it has just been a true thrill to watch this handsome, charming individual grow into the man and the president that he is,” she said, as she reached out to playfully touch the president’s face, sparking laughter from the crowd.

Praising his compassion and courage, the first lady introduced the president as the “love of her life.”

Obama, who was sworn in for a second term in a small White House ceremony earlier today, kept his remarks short, noting he has another big speech to deliver Monday.

“There are a limited amount of good lines and you don’t want to use them all up tonight,” he joked.

Because the Constitutionally mandated date for the inauguration, Jan. 20, fell on a Sunday this year, the traditional, public ceremony was delayed until Monday.

Saving the best for his official inaugural address, the president instead dedicated the bulk of his remarks to thanking supporters for their hard work and dedication to getting him re-elected.

“You understood this was not just about a candidate; it was not just about Joe Biden or Barack Obama. This was about us, who we are as a nation, what values we cherish, how hard we’re willing to fight to make sure that those values live not just for today but for future generations,” he said.

“All of you here understood and were committed to the basic notion that when we put our shoulders to the wheel of history, it moves… It moves forward. And that’s part of what we celebrate when we come together for inauguration,” he said.

SHOWS: World News

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Algeria ends desert siege with 23 hostages dead

ALGIERS/IN AMENAS, Algeria (Reuters) - Algerian troops ended a siege by Islamist militants at a gas plant in the Sahara desert where 23 hostages died, with a final assault which killed all the remaining hostage-takers.

Believed to be among the 32 dead militants was their leader, Abdul Rahman al-Nigeri, a Nigerien close to al Qaeda-linked commander Mokhtar Belmokhtar, presumed mastermind of the raid.

An Algerian interior ministry statement on the death toll gave no breakdown of the number of foreigners among hostages killed since the plant was seized before dawn on Wednesday.

Details are only slowly emerging on what happened during the siege, which marked a serious escalation of unrest in northwestern Africa, where French forces are ratcheting up a war against Islamist militants in neighboring Mali.

Algeria's interior ministry said on Saturday that 107 foreign hostages and 685 Algerian hostages had survived, but did not give a detailed breakdown of those who died.

"We feel a deep and growing unease ... we fear that over the next few days we will receive bad news," said Helge Lund, Chief Executive of Norway's Statoil, which ran the plant along with Britain's BP and Algeria's state oil company.

"People we have spoken to describe unbelievable, horrible experiences," he said.

British Prime Minister David Cameron said he feared for the lives of five British citizens unaccounted for at the gas plant near the town of In Amenas, which was also home to expatriate workers from Japanese engineering firm JGC Corp and others.

One American and one British citizen have been confirmed dead. Statoil said five of its workers, all Norwegian nationals, were still missing. Japanese and American workers are also unaccounted for.

The Islamists' attack has tested Algeria's relations with the outside world, exposed the vulnerability of multinational oil operations in the Sahara and pushed Islamist radicalism in northern Africa to center stage.

Some Western governments expressed frustration at not being informed of the Algerian authorities' plans to storm the complex. Algeria, scarred by a civil war with Islamist insurgents in the 1990s which claimed 200,000 lives, had insisted there would be no negotiation in the face of terrorism.

President Barack Obama said on Saturday the United States was seeking from Algerian authorities a fuller understanding of what took place, but said "the blame for this tragedy rests with the terrorists who carried it out."

Official sources had no immediate confirmation of newspaper reports suggesting some of the hostages may have been executed by their captors as the Algerian army closed in for the final assault on Saturday.

One source close to the crisis said 16 foreign hostages were freed, including two Americans and one Portuguese.

BP's chief executive Bob Dudley said on Saturday four of its 18 workers at the site were missing. The remaining 14 were safe.

PLANNED BEFORE FRENCH LANDED IN MALI

The attack on the heavily fortified gas compound was one of the most audacious in recent years and almost certainly planned long before French troops launched a military operation in Mali this month to stem an advance by Islamist fighters.

Hundreds of hostages escaped on Thursday when the army launched a rescue operation, but many hostages were killed.

Before the interior ministry released its provisional death toll, an Algerian security source said eight Algerians and at least seven foreigners were among the victims, including two Japanese, two Britons and a French national. One British citizen was killed when the gunmen seized the hostages on Wednesday.

The U.S. State Department said on Friday one American, Frederick Buttaccio, had died but gave no further details.

U.S. Defense Secretary Leon Panetta said nobody was going to attack the United States and get away with it.

"We have made a commitment that we're going to go after al Qaeda wherever they are and wherever they try to hide," he said during a visit to London. "We have done that obviously in Afghanistan, Pakistan, we've done it in Somalia, in Yemen and we will do it in North Africa as well."

Earlier on Saturday, Algerian special forces found 15 unidentified burned bodies at the plant, a source told Reuters.

Mauritanian news agencies identified the field commander of the group that attacked the plant as Nigeri, a fighter from one of the Arab tribes in Niger who had joined the Algerian Salafist Group for Preaching and Combat (GSPC) in early-2005.

That group eventually joined up with al Qaeda to become Al Qaeda in the Islamic Maghreb (AQIM). It and allied groups are the targets of the French military operation in Mali.

The news agencies described him as "one of the closest people" to Belmokhtar, who fought in Afghanistan and then in Algeria's civil war of the 1990s. Nigeri was known as a man for "difficult missions", having carried out attacks in Mauritania, Mali and Niger.

NO NEGOTIATION

Britain, Japan and other countries have expressed irritation that the Algerian army assault was ordered without consultation.

But French President Francois Hollande said the Algerian military's response seemed to have been the best option given that negotiation was not possible.

"When you have people taken hostage in such large number by terrorists with such cold determination and ready to kill those hostages - as they did - Algeria has an approach which to me, as I see it, is the most appropriate because there could be no negotiation," Hollande said.

The apparent ease with which the fighters swooped in from the dunes to take control of an important energy facility, which produces some 10 percent of the natural gas on which Algeria depends for its export income, has raised questions over the country's outwardly tough security measures.

Algerian officials said the attackers may have had inside help from among the hundreds of Algerians employed at the site.

Security in the half-dozen countries around the Sahara desert has long been a preoccupation of the West. Smugglers and militants have earned millions in ransom from kidnappings.

The most powerful Islamist groups operating in the Sahara were severely weakened by Algeria's secularist military in the civil war in the 1990s. But in the past two years the regional wing of al Qaeda gained fighters and arms as a result of the civil war in Libya, when arsenals were looted from Muammar Gaddafi's army.

(Additional reporting by Balazs Koranyi in Oslo, Estelle Shirbon and David Alexander in London, Brian Love in Paris; Writing by Giles Elgood and Myra MacDonald)

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Scope to expand health screening programmes for elderly: Koh Poh Koon

SINGAPORE: The People's Action Party (PAP) candidate for the Punggol East by-election Dr Koh Poh Koon said he plans to set up a wellness centre for the elderly to help senior residents age actively.

He said there is scope to expand health screening and preventive programmes for the elderly in the ward.

Dr Koh told reporters that plans are still in early stages but the centre will be built as part of the new Community Centre, to be located near Rivervale Plaza.

He said fundraising for the new centre has reached 50 per cent.

Dr Koh added that he will push forward on this effort if and when he is elected MP for the area.

- CNA/ck

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Congress calls on secular and progressive forces to unite

JAIPUR: The draft Jaipur declaration of Congress party has called on all secular and progressive forces to unite in ideological battle against those who polarize and divide society.

The draft says that the party will go to the people on the basis of performance of UPA govt, the promise of stability and good governance and restatement of its core values.

Addressing the party meeting on the last day at the chintan shivir on Sunday, Congress president Sonia Gandhi outlined the road ahead for the party.

Expressing happiness at the large participation of youth leaders, she said it was a positive sign for the party.

Sonia said the party should deal with corruption effectively.

She stressed the need for electoral reforms.

The Congress president said she will press for passage of Women's Reservation Bill.

The barbaric Delhi gang-rape case has shaken the conscience of the country, Sonia said.

She said the death of the victim will not go in vain.

Sonia slammed the comments against women made by political leaders in the recent past.

(With inputs from PTI)

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Lilly drug chosen for Alzheimer's prevention study

Researchers have chosen an experimental drug by Eli Lilly & Co. for a large federally funded study testing whether it's possible to prevent Alzheimer's disease in older people at high risk of developing it.

The drug, called solanezumab (sol-ah-NAYZ-uh-mab), is designed to bind to and help clear the sticky deposits that clog patients' brains.

Earlier studies found it did not help people with moderate to severe Alzheimer's but it showed some promise against milder disease. Researchers think it might work better if given before symptoms start.

"The hope is we can catch people before they decline," which can come 10 years or more after plaques first show up in the brain, said Dr. Reisa Sperling, director of the Alzheimer's center at Brigham and Women's Hospital in Boston.

She will help lead the new study, which will involve 1,000 people ages 70 to 85 whose brain scans show plaque buildup but who do not yet have any symptoms of dementia. They will get monthly infusions of solanezumab or a dummy drug for three years. The main goal will be slowing the rate of cognitive decline. The study will be done at 50 sites in the U.S. and possibly more in Canada, Australia and Europe, Sperling said.

In October, researchers said combined results from two studies of solanezumab suggested it might modestly slow mental decline, especially in patients with mild disease. Taken separately, the studies missed their main goals of significantly slowing the mind-robbing disease or improving activities of daily living.

Those results were not considered good enough to win the drug approval. So in December, Lilly said it would start another large study of it this year to try to confirm the hopeful results seen patients with mild disease. That is separate from the federal study Sperling will head.

About 35 million people worldwide have dementia, and Alzheimer's is the most common type. In the U.S., about 5 million have Alzheimer's. Current medicines such as Aricept and Namenda just temporarily ease symptoms. There is no known cure.

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Online:

Alzheimer's info: http://www.alzheimers.gov

Alzheimer's Association: http://www.alz.org

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Follow Marilynn Marchione's coverage at http://twitter.com/MMarchioneAP

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